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[DOI] [PMC free article] [PubMed] [Google Scholar] 59.Shi H, Mao X, Zhong Y, Liu Y, Zhao X, Yu K

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A clear improvement of ataxia by 44% and 20% was observed in two patients, respectively, as measured by the ICARS score, an objective assessment that quantifies the magnitude of improvement in progressive ataxias, with a score of 5%-20% considered as substantial in providing a clinical impact

Neurol: Neuroimmunol Neuroinflammat 8:e981 Platero JL, Cuerda-Ballester M, Ibez V, Sancho D, Lopez-Rodrguez MM, Drehmer E, de La Rubia Ort JE (2020) The impact of coconut oil and epigallocatechin gallate on the levels of IL-6, anxiety and disability in multiple sclerosis patients

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Later, another group reported that the excessive production of NO, TNF- , and IL-1 induced by lipopolysaccharide in BV-2 cells was inhibited by celastrol