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While short-term LC supplementation has demonstrated positive effects, including increased endurance, improved hepatic fat metabolism, and myocardial stability, evidence indicates that the prolonged supplementation may pose risks, particularly for individuals with pre-existing cardiovascular or renal conditions

Results of a comparative trial of amsacrine/cytarabine/thioguanine (AAT) and daunorubicin /cytarabine /thioguanine (DAT) in patients with untreated acute non lymphocytic leukemia (ANLL): Results of the L 16M protocol

An important precursor in the synthesis of the ribose backbone, essential for both purines and pyrimidines, comes from ribose-5-phosphate, an intermediate of the pentose-phosphate pathway (PPP) (31)

10.1111/ppl.13024 36 LeeY

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This reduction can be linked to a higher susceptibility to oxidative stress, inflammation, and various diseases, as detailed in research from the European Journal of Nutrition