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Synthesis and recycling of tetrahydrobiopterin in endothelial function and vascular disease PMC Therapeutic strategies to increase NO effect. BH4, tetrahydrobiopterin; Download Scientific Diagram Rhythmic metabolites in the urea cycle, neurotransmitter metabolism Download Scientific Diagram De novo synthesis and regeneration of BH4. GTPCH, GTP cyclohydrolase I; Download Scientific Diagram Nitric Oxide SynthaseNOS 3 ENDOTHELIAL CELLS: "Under physiological conditions, following binding of Tetrahydrobiopterin (BH4) to the oxidase domain of Nitric Oxide Synthase [NOS], the enzyme Nitric Oxide Synthase (NOS) is activated by Tetrahydrobiopterin an overview ScienceDirect Topics
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