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CoQ10 a super-vitamin: Review on application and biosynthesis" 3

Blood (2007) 109(11):475360

An age- and IOP-dependent decline in retinal NAD was first identified in DBA/2J mice as a feature of early disease ( Gpnmb and Tyrp1 genes result in iris pigment dispersion which block the trabecular meshwork causing an elevated IOP

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