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Two of three cases of angiolipomas in one publication suggest a neoplastic nature for these tumors due to deletion of parts of chromosome 13, a region containing the retinoblastoma gene, a tumor suppressor gene (198)

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A small clinical study with 20 healthy volunteers demonstrated that Pycnogenol intake for four weeks increased gene expression of hyaluronic acid synthase by 44% (25)

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The resulting data were indicative of the suppressive impact of TFR2 on the viability of TNBC cells by inducing ferroptosis