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ECM remodeling increases the hardness of tumors, which is mainly caused by the increase of ECM components, especially collagen and hyaluronic acid (80) (80)

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Abbreviations NS : Nigella sativa seeds FBW : Final body weight BWG : Body weight gain TDMI : Total dry matter intake FCR : Feed conversion ratio TAC : Total antioxidant capacity CAT : Catalase IL-10 : Interleukin 10 IL-4 : Interleukin 4 MDA : Malondialdehyde HGB : Hemoglobin RBCs : Red blood cell HCT : Hematocrit MCHC : Mean corpuscular hemoglobin concentration MCV : Mean corpuscular volume PLAT : Platelet MCH : Mean corpuscular hemoglobin WBCs : White Blood Cell LYM : Lymphocytes MON : Monocytes TC : Total cholesterol AST : Aspartate ALT : Alanine transaminases TG : Triglyceride HDL : High-density lipoprotein VLDL : Very low-density lipoprotein LDL : Low-density lipoprotein References Abd El-Hafeez AM, Ali MA, El-Hamd A, Mohamed A, Wahba AA, El-Sayed KM (2014) Productive performance, immune status and metabolic activity of suckling bovine calves treated with Nigella sativa oil

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