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Furthermore, as mentioned earlier, under certain circumstances, low oxygen conditions lead to dimer formation between BMAL1 and HIF-1, which then bind with HREs for transcriptional activation

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These results indicated that YAP1 promoted cellular glutamine uptake and metabolism to GSH

It remains unclear whether a long-term treatment of BML-260 would induce NAFLD or autoimmune diseases

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Brenner, J