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Studies in rat frontal cortex found that intranasal administration (300 mcg/kg) produced significant changes in the mRNA expression of 45 genes involved in GABAergic neurotransmission within one hour of administration[2]

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In research settings, GHK-Cu is studied for its involvement in collagen-related signaling, antioxidant response, and cellular regeneration pathways, making it relevant in experimental models focused on structural integrity and tissue dynamics

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