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Rating: 4.893700000000001 (8 reviews)

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2012 Apr 1;125(Pt 7):1837

Impaired crosstalk with lysosomes and autophagosomes disrupted mitophagy and favored the persistence of dysfunctional mitochondria, defective vacuolar processing, and inflammatory amplification

therefore, Acs1 inhibitors could also be used in combination with fluconazole to both reduce the emergence of resistance and improve efficacy

144 , 10581073.e3 (2019)

However, the sample size of this study is too small, so more pharmacodynamics studies should be carried out in the future, and then mechanism studies should be carried out