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Introduction Enzymes are a class of biological macromolecules with catalytic activity and specific spatial conformation in organisms, and they are widely used in chemical industry, medicine, food, and energy ( Candida rugosa lipase (CRL) is a lipase with important application value, which has high activity and specificity and can be widely used in chemical, cosmetic, food, and other applications ( Immobilization can improve the operational stabilization and activity of enzymes and sometimes can even modulate the selectivity of enzymes by immobilization on functional supports ( 3 O 4 and natural organic polymers with the characteristics of excellent biocompatibility, high mechanical stability, and good recyclability have received more and more attention and obtained good applications in enzyme immobilization ( 3 O 4 ) that consisted of magnetic graphene oxidechitosan (GO-CS) and magnetite nanoparticles (Fe 3 O 4 ) and that was activated with glutaraldehyde (GA) to immobilize CRL

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On the other hand, it is assumed that VPA primarily attenuates seizures by indirectly inhibiting GABA metabolism, preventing the breakdown of GABA, leading to an increase in GABA quantity, allowing it to exert more effect as an inhibitory neurotransmitter, which thus reduces neuronal activity 14

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Gu S, Wang W, Ye G, Chen C, Zhou Y, Guo L, et al

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pantotenska kiselina (kao dekspantenol) Uporaba: Uzimaju se 1 do 2 velike lice (15-30 ml) na dan, po mogunosti na prazan eludac

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