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According to a recent paper authored by Professor Davids and published in the South African Medical Journal , IV glutathione treatments have so far only been deemed safe when administered for a few weeks at the most, with further studies needed to determine the safety of long-term use

10.1016/j.cell.2004.05.008 Cell 141 RochaE

In fact, an alternative explanation of hyperhomocysteinemia without a concomitant increase in GSH is as follows: Excess homocysteine is exported out of the cells to avoid toxicity, and this manifests clinically as hyperhomocysteinemia

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Stem Cell Rev Rep 2021 Jun;17(3):999-1013

Clinical criteria for subtyping Parkinsons disease: biomarkers and longitudinal progression