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A herbal drug may contain many phytochemicals, that could interact synergistically and multi-functionally, making the safety and efficacy assessment very difficult (World Health Organization [WHO], 2004)

5B) due to it covalently modifying the enzyme vs

Obeid R, Schn C, Derbyshire E, et al

First, the spatial organization and regulation of Mn transporters across polarized tissues such as the intestine, liver, and brain are incompletely defined