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The SNPs involved include variations in the following genes: SOD2 (thymine to cytosine nucleotide change) CAT (adenine to thymine nucleotide change) GPX4 (thymine to adenine nucleotide change) NOS1 (cytosine to thymine nucleotide change) NOS2 (cytosine to thymine nucleotide change) NOS2 (guanine to cytosine nucleotide change) The results showed a significant correlation between the SOD2 SNP and the occurrence of stroke

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(5) It has been hypothesized that the underlying mechanisms for this observed phenomena may involve the presence of the tripeptide sequence Gly-His-Lys as a fragment typically released during the hydrolysis process of collagen