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Furthermore, the treatment was well-tolerated, with good overall compliance

Naturally occurring skin-whitening agents for inhibiting melanogenesis Naturally occurring skin-whitening agents exert their effects by regulating melanin production through a number of mechanisms, including inhibiting the expression and activity of TYR and suppressing the uptake and distribution of melanosomes

Phytochemistry 116:6977 Cobbett CS, May MJ, Howden R, Rolls B (1998) The glutathione- deficient, cadmium-sensitive mutant, cad2-1, of Arabidopsis thaliana is deficient in gamma-glutamylcysteine synthetase