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FBXO22-NSD2 interactions facilitate cooperative binding for efficient UNC10088-dependent ubiquitination Based on this structure, we made several mutants to test the contributions of individual interactions

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Since EpCAM and HGF/c-Met are involved in important signaling pathways in various cancers, the purpose of this study is to elucidate the interplay between these molecules, tumor microenvironment, and intracellular pathways