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Additional functions of GST include nucleophilic addition of GSH to toxic compounds, reduction of hydroperoxides, and as a carrier protein (ligandins) of specific organic molecules that result in the inactivation and immobilization of these molecules

Myth: Tirzepatide is only for people with a lot of weight to lose. Fact: Eligibility is determined by a licensed provider based on your BMI and underlying health conditions

This pricing gap largely reflects tirzepatide being a newer medication with a dual-agonist patent, whereas semaglutide is a more established drug with potential generics on the horizon around 2028

DOI:10.1083/jcb.201708007 52

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Ruvolo PP, R-Y W, Ruvolo VR, Jacamo R, McQueen T, Borthakur G, Qiu YH, Kevin R Coombes KR, Zhang N, Shpall EJ, Champlin RE, Garzon R, Marcucci G, Croce CM, Konopleva M, Andreeff M , Kornblau SM