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The World Anti-Doping Agency (WADA) has listed it under S0 Unapproved Substances due to its potential performance-enhancing effects

When counseling patients, its helpful to contextualize risk: emphasize that most adverse effects are mild and short-lived, but that serious complications, although rare, can occur without proper screening

Pros/cons: Z-drugs work fast but can impair architecture, cause next-day hangover, and carry dependence risk

2012;4(8, article 70) doi: 10.1186/gm371

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