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This leads to the amplification of GGT transcription

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infantum type 2 NADH dehydrogenase (NDH2) for a group of ubiquinone analogs including a 4-aminoquinoline, phthalazine, quinolone, and other N -heteroarenes (Stevanovic et al., 2018)

AR ubiquitination induced by the curcumin analog suppresses growth of temozolomide-resistant glioblastoma through disrupting GPX4-Mediated redox homeostasis

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This indicates that survival is critically dependent upon GSH, and therefore is not being sustained by an alternative Trx-disulfide reductase, such as by repurposing of either the mitochondrial TrxR2 or the testis-specific Tgr (TrxR3) [48, 109]