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GPX4 is an antioxidant enzyme that primarily reduces lipid peroxides, especially lipid hydroperoxides, into their corresponding alcohols, thus protecting cell membranes from oxidative damage [39]

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No potential mutagenicity of tesamorelin acetate was revealed in a battery of tests including induction of gene mutations in bacteria (the Ames test), gene mutations in mammalian cells grown in vitro (hamster CHOK1 cells), and chromosomal damage in intact animals (bone marrow cells in mice)

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