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The following inclusion criteria were used for screening of the identified articles: stimulation methods included manual acupuncture (MA), EA, TAES and TEAS, and the main diseases studied included cognitive impairment caused by stroke which are related to microbiota-gut-brain-axis

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It follows the same regulatory arc as BPC-157 and TB-500: Category 2 placement in 2023, removal from Category 2 in April 2026, and formal PCAC review scheduled for July 23, 2026

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