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Direct Antioxidant Activity Glutathione donates electrons to neutralize reactive oxygen species (ROS) including hydrogen peroxide (H2O2), lipid peroxides, and hydroxyl radicals

These findings suggest that blocking ferroptosis may shield corneal epithelial cells from oxidative stress-related cell death when GPX4 activity is compromised (153)

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FIGURE 7 Lower levels of vitamin E supplementation can improve the non-enzymatic antioxidant activity through a lower concentration of malondialdehyde and a higher content of glutathione ( In a recent dose-response study of Zhang et al