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38 A randomized trial of older adults found that a 16-week course of GlyNAC reduced waist circumference and improved several metabolic markers

It is chemically composed of three amino acids: glutamine, cysteine, and glycine

Elevated intracellular cAMP levels activate protein kinase A (PKA), which phosphorylates multiple downstream targets including transcription factors like CREB (cAMP response element-binding protein)

Despite the differing compartmentalization of each forms of SOD in the mitochondria, cytoplasm and extracellular matrix, they all share the function of neutralizing ROS (Miao and St Clair, 2009)