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Using a well-established model of oxidatively damaged IVF mouse embryos, we applied the iTRAQ method to identify proteins differentially expressed between control and oxidatively damaged zygotes and explored the possible tumorigenic mechanisms, especially with regard to the effects of oxidative damage on ribosome biogenesis closely related to tumorigenesis

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Recent research has taken advantage of the neuroprotective properties of indole-containing compounds such as melatonin, which is reduced in AD patients (Rossotti and Rossotti 1965), by combining the indole structure with other bioactive components (e.g., 8-hydroxyquinolines and tacrine) to create compounds with multiple therapeutic benefits aimed at treating AD (Gans et al

Breast cancer Res