In HD, a compromised function of astrocytes can elicit a variety of cellular mechanisms, including transcriptional dysregulation, impairment of mitochondrial function, synaptic dysfunction, endoplasmic reticulum (ER) stress, and reduced levels of trophic factors, which cause pathological injury to the medium spiny neurons (Caron et al., 2018
- 30x Concentrated Berberine Extract
YangKLiuXLiuYWangXCaoLZhangXet alDC-SIGN and toll-like receptor 4 mediate oxidized low-density lipoprotein-induced inflammatory responses in macrophages
Structure-guided development of heterodimer-selective GPCR ligands
Micheau O, Solary E, Hammann A, Martin F and Dimanche-Boitrel MT
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