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Description

Tanshinone IIA (TIIA) enhances NRF2 binding and transcriptional activation at the promoters of target transporter proteins BSEP and NTCP through TET2-mediated demethylation of NRF2

Aging, along with environmental exposures and genetic mutations, continues to represent one of the biggest risk factors for a host of diseases, including neurodegenerative and other neurological disorders

Alpha lipoic acid (50mg) is a naturally occurring antioxidant compound involved in energy metabolism

14 Translational challenges and opportunities The clinical translation of GSH-responsive nanomedicine faces several important barriers

Mayatepek E, Badiou S, Bellet H, Lehmann WD: A patient with neurological symptoms and abnormal leukotriene metabolism: a new defect in leukotriene biosynthesis