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recently used stable-isotope tracing metabolomics with 13 C 5 -valine confirming multiple previously unknown conjugations between 3-hydroxypropionate and amino acids, and discovered a shunt-within-a-shunt metabolic pathway for propionate degradation in Caenorhabditis elegans 24

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In a genome-wide association study (GWAS) involving more than 140,000 individuals of European descent, uric acid receptors encoded by twenty-eight chromosomal genes were discovered to impact plasma uric acid levels