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Sustained intra-articular reactive oxygen species scavenging and alleviation of osteoarthritis by biocompatible amino-modified tantalum nanoparticles

The standard schedule keeps each injection at 3.2 mg: daily in weeks 14, five times per week in weeks 58, and two or three times weekly in weeks 912

The presence of cysteine, with the thiol group (-SH), gives glutathione a remarkable ability to oxidize, an ability that is used in living systems to neutralize oxidizing substances such as oxygen radicals, preventing the latter from reacting to damage important biological molecules, such as enzymes or nucleic acids

Chitosan-decorated selenium nanoparticles as protein carriers to improve the in vivo half-life of the peptide therapeutic BAY 55-9837 for type 2 diabetes mellitus

These opposing roles of distinct PRDX isoforms suggest that PRDXs function not simply as antioxidant enzymes but as context-dependent determinants of ferroptosis sensitivity

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