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Effect of SNP on BSO-induced ferroptotic cell death To provide additional support for the hypothesis that NO accumulation subsequently leads to ROS and lipid peroxide accumulation in BSO-induced cell death, next we sought to investigate the effect of sodium nitroprusside (SNP), which is known to directly release NO [34], on ROS and lipid peroxide accumulation and ferroptosis in HT22 cells that were jointly treated with BSO and SNP

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