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The guiding principle of phlebotomy should be to improve oxygen delivery by reducing blood viscosity and increasing blood flow rather than restoration of a normal hematocrit

In addition to the hydrochloric acid secreted from the stomach, the properly functioning parietal cells also secrete intrinsic factor, however nothing is bound to the intrinsic factor at this point

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But serious health problems can arise for some individuals taking vitamin B12 at higher dosages

Further studies are warranted to solidify their role in protocols for CTN