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Considering the connection between the cGAS- STING pathway and other pathways, therefore, we can maximally enhance the activation of the cGAS- STING pathway by modulating other pathways

Furthermore, inflammation-driven BBB disruption appears to be a shared feature between AD and PD, with elevated cytokine and oxidative stress responses contributing to vascular damage in both diseases, although the specific molecular pathways involved remain better characterized in AD [98,100,110]

Funnel plot analysis revealed significant bias in the study by Sinha (2007)

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8 and 9) and GSE273757 (Fig