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Aging and the environment affect gamete and embryo potential: can we intervene

Nacystelyn, a novel lysine salt of n-acetylcysteine, to augment cellular antioxidant defence in vitro

Erythrophagocytosis by liver macrophages (Kupffer cells) promotes oxidative stress, inflammation, and fibrosis in a rabbit model of steatohepatitis: implications for the pathogenesis of human nonalcoholic steatohepatitis

doi: 10.1073/pnas.0605390103 218

Overexpression of TFEB can rescue this phenotype by promoting lysosomal biogenesis and A trafficking

Supplementation has been linked to increased expression of slit diaphragm proteins such as nephrin and podocin, as well as reduced tubular injury, possibly through anti-inflammatory and anti-RAAS mechanisms ( Taken together, these findings suggest that vitamin D exerts renal protection in CKD not only through inflammation, oxidative stress, and fibrosis regulation but also via its roles in autophagy, Klotho signaling, and podocyte stability, highlighting its broader therapeutic potential (Figure 3)