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2.15 SYTOX green staining and cell death analysis To assess the neuroprotective potential of inhibiting GLT-1 C-terminal PTMs during OGD, cell death in hippocampal OSCs was quantified using SYTOX Green staining

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The modulation of ferroptosis holds promise in various diseases

Metformin inhibits growth of thyroid carcinoma cells, suppresses self-renewal of derived cancer stem cells, and potentiates the effect of chemotherapeutic agents

Inflammatory mediators, ferroptosis inducers, mechanical overloading, and iron overload increase the accumulation of ROS and lipid peroxidation in chondrocytes, which can lead to chondrocytes ferroptosis and might contribute to the pathogenesis

Ethics Statement Written informed consent was obtained from the patient for publication of this case report and accompanying images