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In the NVU, endothelial cells are primarily responsible for the barrier functionality, with TJs between adjacent cells forming capillary walls in the CNS 9

Certain Medications: Some prescription drugs, like certain anti-seizure medications or even long-term use of other common drugs, can raise GGT levels as your liver works hard to metabolise them

Expression level of glutamine synthetase is increased in hepatocellular carcinoma and liver tissue with cirrhosis and chronic hepatitis B

doi: 10.1186/s11689-017-9207-8 153 ChadwickWAngulo-HerreraICogramPDeaconRJMMasonDJBrownDet al

At the same time 32% of those studied experienced adverse events, including liver dysfunction and one case of anaphylaxis (Alzahrani et al., Cureus 2025, PMID 40013212)

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