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Front Cell And Dev Biol

J Hepatol

Among the ergot-derived dopamine agonists, bromocriptine, marketed as Parlodel, is administered orally

It inhibits the activation of nuclear factor kappa B (NF-B), a transcription factor that drives the expression of pro-inflammatory cytokines

Accordingly, combination therapy using probenecid as an adjuvant with NAC represents a logical neurotherapeutic strategy for treatment of TBI (and other CNS diseases)