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Description

XG: Conceptualization, Funding acquisition, Supervision, Writing review & editing

Research background

Oncogene 34 , 44484459 (2015)

19,20 The glutathione S-transferase mu 1 ( GSTM1 ), glutathione S-transferase theta 1 ( GSTT1 ), and glutathione S-transferase pi 1 ( GSTP1 ) genes are polymorphic and some allelic variants cause enzyme deficiency

DOI:10.1016/0959-8049(95)00310-F [ Links ] 30

Considering that, compared to the other drugs used in CVS, CoQ10 has a very favorable safety profile [13] and after a very positive experience (complete disappearance of CVS in a very severe patient only treated by CoQ), we designed this study to evaluate the efficacy of CoQ10 in monotherapy as the first line treatment of CVS