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With respect to the deiodinases, a healthy liver predominantly expresses D-1, with very low expression of D-3

Resolvins, another important group of pro-resolving lipid mediators, mainly originate from polyunsaturated fatty acids such as omega-3 fatty acids

In NASH, mitochondrial, peroxisomal, and microsomal sources generate excessive ROS, leading to oxidative damage of nuclear and mitochondrial DNA and promoting apoptosis

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Xingang Guan, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

It is mainly found in foods of animal origin (meat and dairy), and the body can also synthesise it in limited amounts