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47 These findings may prove to be particularly relevant as tocilizumab, an IL-6 intervention therapy, is currently being used to treat COVID-19 as well as autoimmune and other severe inflammatory conditions

However, an imbalance in this protective mechanism can lead to damage in cell molecules, such as DNA, proteins and lipids, resulting in cell death by necrotic and apoptotic processes (Hussain et al., 2016)

Storage method and period of stock solution: -80C, 2 years

Negative controls were prepared by omitting the primary antibodies

We observed that the bacterial load in brain is curiously high, suggesting that the pneumococcal infections could be reached by bacteremia but also through a nonhematogenous route [39, 40]